Foxa1 and Foxa2 are closely related family members of the Foxa group of transcription
factors that are coexpressed in subsets of respiratory epithelial cells throughout lung
morphogenesis. Shared patterns of expression, conservation of DNA binding, and
transcriptional activation domains indicate that they may serve complementary functions in
the regulation of gene expression during lung morphogenesis. Whereas branching
morphogenesis of the fetal lung occurs normally in the Foxa2 Δ/Δ and Foxa1–/–mice …