Acne is one of the most prevalent diseases in dermatology: Millions of people worldwide
experience this distressing condition. To determine the appropriate therapeutic strategy,
there is a strong need for a standardized classification system of acne. The exact molecular
mechanism of action of isotretinoin is not completely understood; however, oral isotretinoin
targets simultaneously at all major mechanisms of acne pathogenesis. Various mass media
reports about the risk of teratogenicity and depression from isotretinoin usage as well as the …