[HTML][HTML] Cannabinoids Δ9-tetrahydrocannabinol and cannabidiol differentially inhibit the lipopolysaccharide-activated NF-κB and interferon-β/STAT proinflammatory …
Cannabinoids have been shown to exert anti-inflammatory activities in various in vivo and in
vitro experimental models as well as ameliorate various inflammatory degenerative
diseases. However, the mechanisms of these effects are not completely understood. Using
the BV-2 mouse microglial cell line and lipopolysaccharide (LPS) to induce an inflammatory
response, we studied the signaling pathways engaged in the anti-inflammatory effects of
cannabinoids as well as their influence on the expression of several genes known to be …
vitro experimental models as well as ameliorate various inflammatory degenerative
diseases. However, the mechanisms of these effects are not completely understood. Using
the BV-2 mouse microglial cell line and lipopolysaccharide (LPS) to induce an inflammatory
response, we studied the signaling pathways engaged in the anti-inflammatory effects of
cannabinoids as well as their influence on the expression of several genes known to be …