Velocity of radial expansion of contrast-enhancing gliomas and the effectiveness of radiotherapy in individual patients: a proof of principle

KR Swanson, HLP Harpold, DL Peacock, R Rockne… - Clinical oncology, 2008 - Elsevier
AIMS: The initial aims were to use recently available observations of glioblastomas (as part
of a previous study) that had been imaged twice without intervening treatment before
receiving radiotherapy in order to obtain quantitative measures of glioma growth and
invasion according to a new bio-mathematical model. The results were so interesting as to
raise the question whether the degree of radio-sensitivity of each tumour could be estimated
by comparing the model-predicted and actual durations of survival and total numbers of …