Successful intestinal transplantation for microvillus inclusion disease

MM Oliva, JA Perman, JM Saavedra… - Gastroenterology, 1994 - Elsevier
MM Oliva, JA Perman, JM Saavedra, J Young-Ramsaran, KB Schwarz
Gastroenterology, 1994Elsevier
Microvillus inclusion disease is a rare congenital disorder that presents with severe diarrhea
in the newborn period. Multiple therapeutic attempts to control the diarrhea have failed,
leading to a chronic dependence on parenteral nutrition and a high infant mortality. This
report presents the first child with microvillus inclusion disease in whom small bowel
transplantation has been successful, allowing for the administration of total caloric
requirements via the enteral route.
Abstract
Microvillus inclusion disease is a rare congenital disorder that presents with severe diarrhea in the newborn period. Multiple therapeutic attempts to control the diarrhea have failed, leading to a chronic dependence on parenteral nutrition and a high infant mortality. This report presents the first child with microvillus inclusion disease in whom small bowel transplantation has been successful, allowing for the administration of total caloric requirements via the enteral route.
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