Accuracy and precision of PIXImus densitometry for ex vivo mouse long bones: comparison of technique and software version
GEL Franco, TK O'Neil, SJ Litscher… - Journal of Clinical …, 2004 - Elsevier
Many densitometric studies in mice assess bone mineral density (BMD) at specified regions
of interest, often using ex vivo specimens. In the present study, we sought to determine the
precision and accuracy of ex vivo densitometry of mouse bones, comparing two software
versions and two data acquisition techniques. The newer software allows manual
adjustment of the threshold value for bone, improving the ability to analyze bone edges
correctly. Root mean square standard deviations were 2–3 mg/cm2, with coefficients of …
of interest, often using ex vivo specimens. In the present study, we sought to determine the
precision and accuracy of ex vivo densitometry of mouse bones, comparing two software
versions and two data acquisition techniques. The newer software allows manual
adjustment of the threshold value for bone, improving the ability to analyze bone edges
correctly. Root mean square standard deviations were 2–3 mg/cm2, with coefficients of …