Morphological studies on normal and diseased human muscle in culture

A Bishop, B Gallup, Y Skeate, V Dubowitz - Journal of the neurological …, 1971 - Elsevier
Normal and diseased human muscle, obtained by biopsy, has been successfully grown in
tissue culture and has differentiated through multinucleate myoblast and myotube stages
and has also developed cross-striations. Comparative studies have been made of the
normal and diseased muscle in vitro to try to detect changes comparable to those occurring
in the diseased muscle in vivo. The lengths and breadths of multinucleate (differentiated)
cells have been measured, the number of nuclei counted and the results subjected to …