Observation of antigen-dependent CD8+ T-cell/dendritic cell interactions in vivo

BC Schaefer, ML Schaefer, JW Kappler, P Marrack… - Cellular …, 2001 - Elsevier
In order to track hematopoetic cells of all lineages unambiguously at all stages of
development, we have developed C57BL/6 mice that express a transgene coding for green
fluorescent protein (GFP) under control of the human ubiquitin C promoter. These mice,
called UBI-GFP/BL6, express GFP in all tissues examined, with high levels of GFP
expression observed in hematopoetic cells. UBI-GFP/BL6 mice are unique in that B cells, T
cells, and dendritic cells have distinct levels of GFP fluorescence. In cell transfer …