Role of the platelet chemokine platelet factor 4 (PF4) in hemostasis and thrombosis

MA Kowalska, L Rauova, M Poncz - Thrombosis research, 2010 - Elsevier
Chemokines are a family of small proteins that have significant roles in inflammation,
angiogenesis and cellular homing. Since inflammation and hemostasis/thrombosis have
multiple overlapping roles and pathways, one could expect that some chemokines would
also have biologically significant roles in hemostasis/thrombosis as well. This would
especially be true for chemokines that are localized solely or predominantly within platelets
and released in large amounts at sites of platelet activation such as platelet factor 4 (PF4 …