[HTML][HTML] Platelets an inflammatory force in transplantation

CN Morrell, H Sun, AM Swaim, WM Baldwin - American Journal of …, 2007 - Elsevier
Platelet interactions with dendritic cells, T cells and B cells have been best studied in
vasculitis and atherosclerosis, but similar mechanisms may contribute to acute and chronic
vascular lesions in transplants. In acute inflammation, platelets adhere to vessels and
release mediators that increase endothelial cell activation and leukocyte recruitment.
Adherent platelets can also augment antibody and cellular immune responses. Activated
platelets recruit T cells and initiate a feedback loop. In this loop, platelets secrete …