[HTML][HTML] Double PHD fingers protein DPF2 recognizes acetylated histones and suppresses the function of estrogen-related receptor α through histone deacetylase 1
R Matsuyama, I Takada, A Yokoyama… - Journal of biological …, 2010 - ASBMB
Estrogen-related receptor α (ERRα) is a member of the nuclear receptor superfamily and
regulates many physiological functions, including mitochondrial biogenesis and lipid
metabolism. ERRα enhances the transactivation function without endogenous ligand by
associating with coactivators such as peroxisome proliferator-activated receptor γ
coactivator 1 α and β (PGC-1α and-β) and members of the steroid receptor coactivator
family. However, the molecular mechanism by which the transactivation function of ERRα is …
regulates many physiological functions, including mitochondrial biogenesis and lipid
metabolism. ERRα enhances the transactivation function without endogenous ligand by
associating with coactivators such as peroxisome proliferator-activated receptor γ
coactivator 1 α and β (PGC-1α and-β) and members of the steroid receptor coactivator
family. However, the molecular mechanism by which the transactivation function of ERRα is …