Do stable patients with a premorbid depression history have a worse outcome after deep brain stimulation for Parkinson disease?
BACKGROUND: Deep brain stimulation (DBS) has been associated with mood sequelae in
a subset of patients operated on in either the subthalamic nucleus or the globus pallidus
internus for the treatment of Parkinson disease. OBJECTIVE: To compare mood and motor
outcomes in those with and without a presurgical history of depression. METHODS:
Unilateral subthalamic nucleus or unilateral globus pallidus internus DBS patients followed
up for a minimum of 6 months were included. All patients underwent a comprehensive …
a subset of patients operated on in either the subthalamic nucleus or the globus pallidus
internus for the treatment of Parkinson disease. OBJECTIVE: To compare mood and motor
outcomes in those with and without a presurgical history of depression. METHODS:
Unilateral subthalamic nucleus or unilateral globus pallidus internus DBS patients followed
up for a minimum of 6 months were included. All patients underwent a comprehensive …