Deep brain stimulation for refractory obsessive-compulsive disorder
JL Abelson, GC Curtis, O Sagher, RC Albucher… - Biological …, 2005 - Elsevier
BACKGROUND: Neurosurgery (anterior capsulotomy) has been beneficial to many patients
with debilitating, refractory obsessive-compulsive disorder (OCD), but the irreversibility of the
procedure is an important limitation to its use. Nondestructive, electrical stimulation (deep
brain stimulation; DBS) has proven an effective alternative to ablative surgery for
neurological indications, suggesting potential utility in place of capsulotomy for OCD.
METHODS: The effects of DBS for OCD were examined in four patients in a short-term …
with debilitating, refractory obsessive-compulsive disorder (OCD), but the irreversibility of the
procedure is an important limitation to its use. Nondestructive, electrical stimulation (deep
brain stimulation; DBS) has proven an effective alternative to ablative surgery for
neurological indications, suggesting potential utility in place of capsulotomy for OCD.
METHODS: The effects of DBS for OCD were examined in four patients in a short-term …