[HTML][HTML] Decidual cells produce a heparin-binding prolactin family cytokine with putative intrauterine regulatory actions

SMK Alam, T Konno, N Sahgal, L Lu… - Journal of Biological …, 2008 - ASBMB
Pregnancy in mice and rats is associated with the production of a large family of
hormones/cytokines related to prolactin (PRL). The hormones/cytokines are hypothesized to
coordinate maternal and fetal adaptations to pregnancy. In this study, PRL-like protein-J
(PLP-J, also known as PRL family 3, subfamily c, member 1 (Prl3c1)) is shown to be a
product of the uterine decidua and a regulator of postimplantation intrauterine events. PLP-J-
specific antibodies and a series of recombinant PLP-J proteins were generated and used to …