Expression patterns of claudins, tight junction adhesion molecules, in the inner ear

S Kitajiri, M Furuse, K Morita, Y Saishin-Kiuchi, H Kido… - Hearing research, 2004 - Elsevier
Tight junctions (TJs) are indispensable for the establishment of compositionally distinct fluid
compartments in the inner ear, but our knowledge of the claudins, TJ adhesion molecules, in
the inner ear is still fragmentary. We examined the expression and distribution of claudin-1
to claudin-18 (except for claudin-7,-13 and-17) in the inner ear by immunofluorescence
microscopy. In the cochlea, the organ of Corti expressed claudin-1,-2,-3,-9,-10,-12,-14 and-
18. In the stria vascularis, claudin-1,-2,-3,-8,-9,-10,-12,-14 and-18 were expressed in the …