Neurogenic inflammation as a pathway distinct from antigen-driven, immune-mediated
inflammation may play a pivotal role in understanding a broad class of environmental health
problems resulting from chemical exposures. Recent progress in understanding the
mediators, triggers, and regulation of neurogenic inflammation is reviewed. Evidence for and
speculations about a role for neurogenic inflammation in established disorders such as
asthma, rhinitis, contact dermatitis, migraine headache, and rheumatoid arthritis are …