[HTML][HTML] The p53 codon 72 single nucleotide polymorphism lacks a significant effect on implantation rate in fresh in vitro fertilization cycles: an analysis of 1,056 …
G Patounakis, N Treff, X Tao, A Lonczak, RT Scott Jr… - Fertility and sterility, 2009 - Elsevier
OBJECTIVE: To determine whether the p53 codon 72 single nucleotide polymorphism, a
change of the amino acid arginine (Arg) to proline (Pro) resulting from a single nucleotide
mutation of guanine (G) to cytosine (C), has a clinically significant effect on implantation rate
in fresh IVF cycles. DESIGN: Prospective cohort analysis. SETTING: University-affiliated
private IVF center. PATIENT (S): One thousand fifty-six female patients undergoing fresh
nondonor IVF cycles. MAIN OUTCOME MEASURE (S): Embryo implantation rate. RESULT …
change of the amino acid arginine (Arg) to proline (Pro) resulting from a single nucleotide
mutation of guanine (G) to cytosine (C), has a clinically significant effect on implantation rate
in fresh IVF cycles. DESIGN: Prospective cohort analysis. SETTING: University-affiliated
private IVF center. PATIENT (S): One thousand fifty-six female patients undergoing fresh
nondonor IVF cycles. MAIN OUTCOME MEASURE (S): Embryo implantation rate. RESULT …