The dermal-epidermal basement membrane zone (BMZ) is an important epithelial and
stromal interface, consisting of an intricately organized collection of intracellular,
transmembrane, and extracellular matrix proteins. The BMZ has several main functions:
acting as a permeability barrier, forming an adhesive interface between epithelial cells and
the underlying matrix, and controlling cell organization and differentiation. The BMZ of the
skin contains a number of specialized adhesive structures, which help to promote tissue …