Anaemia of chronic disease (ACD), the most frequent anaemia among hospitalized patients,
develops under chronic inflammatory disorders such as chronic infections, cancer or
autoimmune diseases. A number of different pathways contribute to ACD, such as diversion
of iron traffic, a diminished erythropoiesis, a blunted response to erythropoietin,
erythrophagocytosis and bone marrow invasion by tumour cells and pathogens.
Nevertheless, ACD is a reflection of an activated immune system and possibly results from …