Mesenchymal stem cells (MSCs) have been described as being able to give rise to several
quite different mesenchymal cell phenotypes. However, the ability to differentiate is not the
only characteristic that makes these cells attractive for therapeutic purposes. The secretion
of a broad range of bioactive molecules by MSCs, such as growth factors, cytokines and
chemokines, constitutes their most biologically significant role under injury conditions.
Understanding this intricate secretory activity as well as the properties of MSCs in vivo is …