Inducible bronchus-associated lymphoid tissue (iBALT) is an organized tertiary lymphoid
structure that is not pre-programmed but develops in response to infection or under chronic
inflammatory conditions. Emerging research has shown that iBALT provides a niche for T-
cell priming and B-cell education to assist in the clearance of infectious agents, highlighting
the prospect that iBALT may be engineered and harnessed to enhance protective immunity
against respiratory pathogens. Although iBALT formation is associated with several …