The adaptive immune response to colorectal cancer: from the laboratory to clinical practice

NJ Curtis, JN Primrose, GJ Thomas… - European Journal of …, 2012 - Elsevier
INTRODUCTION: Analysis of the adaptive immune system in the microenvironment of
colorectal cancer is suggested to offer new insights into tumour biology and prognostic
information independent of TNM staging. We aimed to review recent findings to investigate
the potential for clinical use. METHODS: Relevant papers were identified through online
searches regarding tumour infiltrating lymphocytes (TIL) in colorectal cancer. Identified
papers were studied, focusing on clinically applicable uses for TIL data in the management …