The bimodal mortality pattern of systemic lupus erythematosus

MB Urowitz, AAM Bookman, BE Koehler… - The American journal of …, 1976 - Elsevier
The changing pattern of mortality in systemic lupus erythematosus (SLE) led to an
examination of the deaths in a long-term systematic analysis of 81 patients followed for five
years at the University of Toronto Rheumatic Disease Unit. During the follow-up 11 patients
died; six patients died within the first year after diagnosis (group I) and five patients died an
average of 8.6 years (from 2.5 to 19.5 years) after diagnosis (group II). In those who died
early, the SLE was active clinically and serologically, and nephritis was present in four. Their …