Programmed cell death in Caenorhabditis elegans

MO Hengartner, HR Horvitz - Current opinion in genetics & development, 1994 - Elsevier
MO Hengartner, HR Horvitz
Current opinion in genetics & development, 1994Elsevier
Programmed cell death in the nematode Caenorhabditis elegans requires the activities of
the genes ced-3 and ced-4 and is antagonized by the activity of the gene ced-9. Cloning of
these C. elegans genes has shown that two of them encode proteins with similarity to
vertebrate cell death genes and has revealed that nematodes and mammals share a
common pathway for programmed cell death.
Abstract
Programmed cell death in the nematode Caenorhabditis elegans requires the activities of the genes ced-3 and ced-4 and is antagonized by the activity of the gene ced-9. Cloning of these C. elegans genes has shown that two of them encode proteins with similarity to vertebrate cell death genes and has revealed that nematodes and mammals share a common pathway for programmed cell death.
Elsevier