Dendritic cells (DCs) are antigen sampling sentinels of the peripheral tissue and specialists
for antigen capture, processing, and presentation to T cells as well as T-cell priming. By
virtue of their mission as antigen samplers, they populate the body surfaces that line the
border of our organism with the environment such as the skin and the mucosa of the
respiratory and the gastrointestinal tract. Although all DCs share some classic features, their
individual organ-specific phenotype and function are ascertained by a complex, dynamic …