[HTML][HTML] Safety and efficacy of TG101348, a selective JAK2 inhibitor, in myelofibrosis

A Pardanani, JR Gotlib, C Jamieson… - Journal of Clinical …, 2011 - ncbi.nlm.nih.gov
A Pardanani, JR Gotlib, C Jamieson, JE Cortes, M Talpaz, RM Stone, MH Silverman…
Journal of Clinical Oncology, 2011ncbi.nlm.nih.gov
Safety and Efficacy of TG101348, a Selective JAK2 Inhibitor, in Myelofibrosis - PMC Back to
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Abstract
Purpose
Myelofibrosis is a myeloid malignancy associated with anemia, splenomegaly, and constitutional symptoms. Patients frequently harbor JAK-STAT activating mutations that are sensitive to TG101348, a selective small-molecule Janus kinase 2 (JAK2) inhibitor.
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