[HTML][HTML] The hemidesmosomal protein bullous pemphigoid antigen 1 and the integrin β4 subunit BInd to ERBIN: molecular cloning of multiple alternative splice …
The bullous pemphigoid antigen 1 (eBPAG1) is a constituent of hemidesmosomes (HDs),
cell-substrate adhesion complexes in stratified epithelia. Although its COOH terminus
interacts with intermediate filaments, its NH 2 terminus is important for its recruitment into
HDs. To identify proteins that interact with the NH 2 terminus of human eBPAG1, we
performed a yeast two-hybrid screen, which uncovered a protein belonging to the LAP/LERP
(for LRRand PDZ domain) protein family with 16 NH 2-terminal leucine-rich repeats and a …
cell-substrate adhesion complexes in stratified epithelia. Although its COOH terminus
interacts with intermediate filaments, its NH 2 terminus is important for its recruitment into
HDs. To identify proteins that interact with the NH 2 terminus of human eBPAG1, we
performed a yeast two-hybrid screen, which uncovered a protein belonging to the LAP/LERP
(for LRRand PDZ domain) protein family with 16 NH 2-terminal leucine-rich repeats and a …