Retinitis pigmentosa (RP) is a genetically and phenotypically heterogeneous group of
diseases that cause blindness. Mutations within the rhodopsin gene account for
approximately 25% of autosomal dominantly inherited RP cases. Therefore, understanding
the mechanisms causing rhodopsin‐mediated RP has a significant health impact. To date,
results from multiple labs indicate that rhodopsin‐mediated RP pathogenesis does not share
a common mechanism of degeneration. There is strong evidence that multiple mechanisms …