Trends and geographic inequalities in the prevalence of Down syndrome in Europe, 1980-1999

H Dolk, M Loane, E Garne, H De Walle… - Revue d'épidémiologie …, 2005 - Elsevier
BACKGROUND: EUROCAT is a network of population-based registries for the
epidemiologic surveillance of congenital anomalies covering approximately one quarter of
births in the European Union. Down syndrome constitutes approximately 8% of cases of
registered congenital anomaly in Europe, with over 7 000 affected pregnancies in the 15
current member states of the European Union each year. In this paper, we aim to examine
trends in the live birth prevalence of Down syndrome in Europe in the light of trends in …