Cytokeratin 20 immunoreactivity distinguishes Merkel cell (primary cutaneous neuroendocrine) carcinomas and salivary gland small cell carcinomas from small cell …
JKC Chan, S Suster, BM Wenig… - The American journal …, 1997 - journals.lww.com
Abstract Cytokeratin 20 (CK20) is a low-molecular-weight cytokeratin (CK) that shows
restricted expression in the gastrointestinal epithelium, urothelium, and Merkel cell. Recent
studies have suggested that since Merkel cell (primary cutaneous neuroendocrine)
carcinomas are consistently CK20-positive, this feature may help to distinguish it from
pulmonary small cell carcinomas. However, only limited numbers of these tumors have been
studied, and the pattern of CK20 expression in other small cell carcinomas has not been …
restricted expression in the gastrointestinal epithelium, urothelium, and Merkel cell. Recent
studies have suggested that since Merkel cell (primary cutaneous neuroendocrine)
carcinomas are consistently CK20-positive, this feature may help to distinguish it from
pulmonary small cell carcinomas. However, only limited numbers of these tumors have been
studied, and the pattern of CK20 expression in other small cell carcinomas has not been …