A critical appraisal of “chronic Lyme disease”

HM Feder Jr, BJB Johnson, S O'Connell… - … England Journal of …, 2007 - Mass Medical Soc
HM Feder Jr, BJB Johnson, S O'Connell, ED Shapiro, AC Steere, GP Wormser…
New England Journal of Medicine, 2007Mass Medical Soc
“Chronic Lyme disease” is often used to explain persistent pain, fatigue, and neurocognitive
symptoms in patients without any evidence of previous acute Lyme disease. Once this
diagnosis is given, prolonged treatment with multiple antimicrobial agents may follow. This
review examines the scientific evidence for chronic borrelia infection and explains the
approach to clinical evaluation and management in patients with a diagnosis of chronic
Lyme disease.
“Chronic Lyme disease” is often used to explain persistent pain, fatigue, and neurocognitive symptoms in patients without any evidence of previous acute Lyme disease. Once this diagnosis is given, prolonged treatment with multiple antimicrobial agents may follow. This review examines the scientific evidence for chronic borrelia infection and explains the approach to clinical evaluation and management in patients with a diagnosis of chronic Lyme disease.
The New England Journal Of Medicine