Risk factors for central serous chorioretinopathy: a case–control study

R Haimovici, S Koh, DR Gagnon, T Lehrfeld, S Wellik… - Ophthalmology, 2004 - Elsevier
R Haimovici, S Koh, DR Gagnon, T Lehrfeld, S Wellik…
Ophthalmology, 2004Elsevier
PURPOSE: To identify systemic factors associated with the development of central serous
chorioretinopathy (CSCR). DESIGN: Retrospective, case–control study. Participants and
controls: 312 cases and 312 controls. RESULTS: By use of a multivariate analysis, the
previously described risk factors, systemic steroid use (odds ratio [OR], 37.1; 95%
confidence interval [CI], 6.2–221.8), and pregnancy (OR, 7.1; 95% CI, 1.0–50.7), were
strongly associated with CSCR. Additional risk factors identified by this study include …
PURPOSE
To identify systemic factors associated with the development of central serous chorioretinopathy (CSCR).
DESIGN
Retrospective, case–control study.
Participants and controls
312 cases and 312 controls.
RESULTS
By use of a multivariate analysis, the previously described risk factors, systemic steroid use (odds ratio [OR], 37.1; 95% confidence interval [CI], 6.2–221.8), and pregnancy (OR, 7.1; 95% CI, 1.0–50.7), were strongly associated with CSCR. Additional risk factors identified by this study include antibiotic use (OR, 6.2; 95% CI, 1.0–37.9), alcohol use (OR, 4.9; 95% CI, 1.5–16.3), untreated hypertension (OR, 3.3; 95% CI, 1.3–8.5), and allergic respiratory disease (OR, 2.5; 95% CI, 1.2–5.1).
CONCLUSIONS
A wide variety of systemic factors are associated with CSCR. Prospective studies are warranted to evaluate the nature and significance of these associations further.
Elsevier