Subfoveal choroidal thickness in fellow eyes of patients with central serous chorioretinopathy

I Maruko, T Iida, Y Sugano, A Ojima, T Sekiryu - Retina, 2011 - journals.lww.com
I Maruko, T Iida, Y Sugano, A Ojima, T Sekiryu
Retina, 2011journals.lww.com
Purpose: To evaluate the subfoveal choroidal thickness in the fellow eyes of patients with
CSC, a disease often associated with choroidal vascular hyperpermeability even in eyes
without subretinal fluid. Methods: In this observational cross-sectional study, we measured
the bilateral subfoveal choroidal thickness in patients with unilateral CSC using enhanced
depth imaging spectral-domain optical coherence tomography. Areas of choroidal vascular
hyperpermeability were visualized with indocyanine green angiography. Results: Sixty-six …
Purpose:
To evaluate the subfoveal choroidal thickness in the fellow eyes of patients with CSC, a disease often associated with choroidal vascular hyperpermeability even in eyes without subretinal fluid.
Methods:
In this observational cross-sectional study, we measured the bilateral subfoveal choroidal thickness in patients with unilateral CSC using enhanced depth imaging spectral-domain optical coherence tomography. Areas of choroidal vascular hyperpermeability were visualized with indocyanine green angiography.
Results:
Sixty-six consecutive Japanese patients (50 men, 16 women; mean age, 52.8 years) with unilateral CSC were examined. The subfoveal choroid in symptomatic eyes was significantly thicker than that in fellow eye (414±109 μm vs. 350±116 μm, P< 0.001, respectively). The subfoveal choroid of eyes with choroidal vascular hyperpermeability was 410±92 μm, which differed significantly (P< 0.001) from the choroid (239±59 μm) of fellow eyes without choroidal vascular hyperpermeability.
Conclusion:
The subfoveal choroid in the fellow eyes of patients with CSC was thicker in the eyes with choroidal vascular hyperpermeability. Enhanced depth imaging spectral-domain optical coherence tomography can assess the effects of choroidal vascular hyperpermeability by measuring the choroidal thickness noninvasively.
Lippincott Williams & Wilkins