[HTML][HTML] When sirtuins and NF-κB collide
G Natoli - Cell, 2009 - cell.com
Cell, 2009•cell.com
Both the sirtuins and certain transcription factors of the NF-κB/Rel family control aging-
associated changes in gene expression. Kawahara et al.(2009) now show a requirement in
mice for the sirtuin SIRT6 in dampening NF-κB-dependent gene expression, thus unveiling a
potential link between inflammation, aging, and metabolism.
associated changes in gene expression. Kawahara et al.(2009) now show a requirement in
mice for the sirtuin SIRT6 in dampening NF-κB-dependent gene expression, thus unveiling a
potential link between inflammation, aging, and metabolism.
Both the sirtuins and certain transcription factors of the NF-κB/Rel family control aging-associated changes in gene expression. Kawahara et al. (2009) now show a requirement in mice for the sirtuin SIRT6 in dampening NF-κB-dependent gene expression, thus unveiling a potential link between inflammation, aging, and metabolism.
cell.com