(Sub) microscopic Plasmodium falciparum gametocytaemia in Kenyan children after treatment with sulphadoxine-pyrimethamine monotherapy or in combination with …

P Schneider, T Bousema, S Omar, L Gouagna… - International journal for …, 2006 - Elsevier
The effects of drugs on Plasmodium falciparum transmission stages may reduce the spread
of parasites in the population and contribute to malaria control. Detailed quantitative studies
on (sub) microscopic gametocytaemia have become feasible with the availability of real-time
Pfs25 quantitative Nucleic Acid Sequence-based Amplification (QT-NASBA), which can be
used to detect gametocyte densities above 20 gametocytes per millilitre from in vitro
cultures. Gametocyte dynamics were investigated in children with uncomplicated P …