Significant progress has been achieved in the last few years concerning the human
immunodeficiency virus (HIV-1) life cycle, mostly in the fields of cellular receptors for the
virus, virus assembly and budding of virus particles from the cell surface. Meanwhile, some
aspects, such as postentry events, virus maturation and the regulatory role of individual viral
proteins remain poorly defined. This review summarizes some recent findings concerning
the role of Gag Pr55 and its proteolytic processing in the HIV-1 life cycle with particular …