Insulin in brain and other extrapancreatic tissues of vertebrates and nonvertebrates

D LE ROITH, SA HENDRICKS, MA LESNIAK… - Advances in Metabolic …, 1983 - Elsevier
Publisher Summary This chapter focuses on insulin in brain and other extrapancreatic
tissues of vertebrates and nonvertebrates. Insulin production is not unique to beta cells of
the vertebrate pancreas. The levels of insulin are high in specific nerves but undetected in
others. Insulin accumulates in nerves proximal to axonal clamps, and electrical stimulation of
nerves results in release of insulin. Insulin content of brain and other extrapancreatic tissues
of mammals is largely independent of the level of plasma insulin, that is, conditions …