[PDF][PDF] The Combination of p53 Mutation and neu/erbB-2 Amplification Is Associated With Poor Survival in Node-Negative Breast Cancer
SB Bull, H Ozcelik, D Pinnaduwage… - Journal of Clinical …, 2004 - academia.edu
SB Bull, H Ozcelik, D Pinnaduwage, ME Blackstein, DAJ Sutherland, KI Pritchard…
Journal of Clinical Oncology, 2004•academia.eduPurpose Increases in neu/erbB-2 have been implicated in breast cancer prognosis, but do
not predict all recurrences. On the basis of evidence that p53 mutation is involved in the
development of human neoplasia, we examined the prognostic value of p53 alterations in
combination with neu/erbB-2 amplification.
not predict all recurrences. On the basis of evidence that p53 mutation is involved in the
development of human neoplasia, we examined the prognostic value of p53 alterations in
combination with neu/erbB-2 amplification.
Purpose
Increases in neu/erbB-2 have been implicated in breast cancer prognosis, but do not predict all recurrences. On the basis of evidence that p53 mutation is involved in the development of human neoplasia, we examined the prognostic value of p53 alterations in combination with neu/erbB-2 amplification.
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