[PDF][PDF] Targeting TGF-β and the extracellular matrix in Marfan's syndrome
Marfan's syndrome is a genetic disorder affecting connective tissues, and it can lead to
death due to aortic defects if left untreated. β-blocker therapy has been used to slow the
progression of this disease. Brooke et al.(2008) now report that combining angiotensin II
receptor blockade by losartan with β-blocker treatment is an effective treatment combination
therapy for this disorder.
death due to aortic defects if left untreated. β-blocker therapy has been used to slow the
progression of this disease. Brooke et al.(2008) now report that combining angiotensin II
receptor blockade by losartan with β-blocker treatment is an effective treatment combination
therapy for this disorder.
Marfan's syndrome is a genetic disorder affecting connective tissues, and it can lead to death due to aortic defects if left untreated. β-blocker therapy has been used to slow the progression of this disease. Brooke et al. (2008) now report that combining angiotensin II receptor blockade by losartan with β-blocker treatment is an effective treatment combination therapy for this disorder.
cell.com