Transport proteins mediating the selective uptake of organic anions into human hepatocytes
include the organic anion transporters SLC21A6 (also termed OATP2, OATP-C, or LST-1)
and SLC21A8 (OATP8). Both transporters are localized to the basolateral membrane of
human hepatocytes. Because of the importance of these transporters for hepatobiliary
elimination, including the removal of bilirubin and its conjugates from the blood circulation,
we have generated monoclonal antibodies for studies on the expression and localization of …