Increased levels of procoagulant tissue factor-bearing microparticles within the occluded coronary artery of patients with ST-segment elevation myocardial infarction …

O Morel, B Pereira, G Averous, A Faure, L Jesel… - Atherosclerosis, 2009 - Elsevier
OBJECTIVE: During myocardial infarction, platelet activation and endothelial apoptosis are
responsible for the release of procoagulant membrane-derived microparticles (MPs) in the
bloodstream. Few data are available on the potential role played by MPs in coronary
atherothrombosis. In the present study, we investigated the levels and cellular origins of MPs
within the occluded coronary artery of patients with ST-segment elevation myocardial
infarction (STEMI) treated by primary angioplasty (PCI). METHODS: A total of 12 patients …