Collagen types I and III, collagen content, GAGs and mechanical strength of human atherosclerotic plaque caps: span-wise variations
MC Burleigh, AD Brigfs, CL Lendon, MJ Davies… - Atherosclerosis, 1992 - Elsevier
Measurements of total collagen, of the ratio of collagen types III/(I+ III) and of sulphated
glycosaminoglycans (GAGs) were compared with mechanical strength for individual
ulcerated and nonulcerated human aortic plaque caps and with intima adjacent to the
plaques. The distributions of the collagen type ratio were similar for both ulcerated and non-
ulcerated plaque caps but different from that of the adjacent intima. The proportions of
different collagen types were not related to fracture stress and are thus unlikely to affect the …
glycosaminoglycans (GAGs) were compared with mechanical strength for individual
ulcerated and nonulcerated human aortic plaque caps and with intima adjacent to the
plaques. The distributions of the collagen type ratio were similar for both ulcerated and non-
ulcerated plaque caps but different from that of the adjacent intima. The proportions of
different collagen types were not related to fracture stress and are thus unlikely to affect the …