[HTML][HTML] Protein oxidation in aging, disease, and oxidative stress
BS Berlett, ER Stadtman - Journal of Biological Chemistry, 1997 - ASBMB
The demonstration that oxidatively modified forms of proteins accumulate during aging,
oxidative stress, and in some pathological conditions has focused attention on physiological
and nonphysiological mechanisms for the generation of reactive oxygen species (ROS) 1
and on the modification of biological molecules by various kinds of ROS. Basic principles
that govern the oxidation of proteins by ROS were established in the pioneering studies of
Swallow (1), Garrison (2, 3), and Scheussler and Schilling (4) who characterized reaction …
oxidative stress, and in some pathological conditions has focused attention on physiological
and nonphysiological mechanisms for the generation of reactive oxygen species (ROS) 1
and on the modification of biological molecules by various kinds of ROS. Basic principles
that govern the oxidation of proteins by ROS were established in the pioneering studies of
Swallow (1), Garrison (2, 3), and Scheussler and Schilling (4) who characterized reaction …