The relative electrophoretic mobility of apo (a) isoforms depends on the gel system: proposal of a nomenclature for apo (a) phenotypes
HG Kraft, A Lingenhel, G Bader, GM Kostner… - Atherosclerosis, 1996 - Elsevier
Genetic apo (a) isoforms were originally defined according to their relative mobility in SDS-
PAGE compared to apoB-100 and were designated as F, B or S1–S4 isotypes. This widely
accepted nomenclature does not accommodate the broad spectrum of apo (a) isoforms (>
30) detected by high resolution SDS-agarose gel electrophoresis. Moreover we here show
that the relative mobilities of apo (a) isoforms depend on the SDS-gel system used.
Comparison of the SDS-PAGE system originally used for phenotyping with SDS-agarose gel …
PAGE compared to apoB-100 and were designated as F, B or S1–S4 isotypes. This widely
accepted nomenclature does not accommodate the broad spectrum of apo (a) isoforms (>
30) detected by high resolution SDS-agarose gel electrophoresis. Moreover we here show
that the relative mobilities of apo (a) isoforms depend on the SDS-gel system used.
Comparison of the SDS-PAGE system originally used for phenotyping with SDS-agarose gel …
