High-throughput shotgun lipidomics by quadrupole time-of-flight mass spectrometry

M Ståhlman, CS Ejsing, K Tarasov, J Perman… - … of Chromatography B, 2009 - Elsevier
Technological advances in mass spectrometry and meticulous method development have
produced several shotgun lipidomic approaches capable of characterizing lipid species by
direct analysis of total lipid extracts. Shotgun lipidomics by hybrid quadrupole time-of-flight
mass spectrometry allows the absolute quantification of hundreds of molecular
glycerophospholipid species, glycerolipid species, sphingolipid species and sterol lipids.
Future applications in clinical cohort studies demand detailed lipid molecule information and …