Infantile spasms in tuberous sclerosis complex

P Curatolo, S Seri, M Verdecchia, R Bombardieri - Brain and Development, 2001 - Elsevier
The high incidence of infantile spasms (IS) and hypsarrhythmia in tuberous sclerosis
complex (TSC) has long been emphasized but it is now clear that infants with TSC show
clinical and EEG differences from those with classical West syndrome. Seizures at onset are
mainly characterized by partial motor seizures and IS. Subtle partial seizures may be
present in the early neonatal period and may precede the onset of IS. Visual recording
techniques have led to significant progress in the classification of seizures associated with …