NKT cells in tumor immunity: opposing subsets define a new immunoregulatory axis
JA Berzofsky, M Terabe - The Journal of Immunology, 2008 - journals.aai.org
The Journal of Immunology, 2008•journals.aai.org
NKT cells are true Ag-specific T cells that also have innate properties and form a bridge
between the innate and adaptive immune systems. Distinct NKT cell subsets play positive
and negative regulatory roles and define a new immunoregulatory axis with broad
implications for tumor immunity and other immunological and disease settings.
between the innate and adaptive immune systems. Distinct NKT cell subsets play positive
and negative regulatory roles and define a new immunoregulatory axis with broad
implications for tumor immunity and other immunological and disease settings.
Abstract
NKT cells are true Ag-specific T cells that also have innate properties and form a bridge between the innate and adaptive immune systems. Distinct NKT cell subsets play positive and negative regulatory roles and define a new immunoregulatory axis with broad implications for tumor immunity and other immunological and disease settings.
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