Neural crest cells contribute to normal aorticopulmonary septation
ML Kirby, TF Gale, DE Stewart - Science, 1983 - science.org
ML Kirby, TF Gale, DE Stewart
Science, 1983•science.orgBy analyzing the hearts of quail-chick chimeras, it was found that neural crest cells at the
level of occipital somites 1 to 3 migrate to the region of the aorticopulmonary septum.
Bilateral removal of this neural crest population prior to migration causes malformation of the
aorticopulmonary septum resulting in common arterial outflow channels or transposition of
the great vessels.
level of occipital somites 1 to 3 migrate to the region of the aorticopulmonary septum.
Bilateral removal of this neural crest population prior to migration causes malformation of the
aorticopulmonary septum resulting in common arterial outflow channels or transposition of
the great vessels.
By analyzing the hearts of quail-chick chimeras, it was found that neural crest cells at the level of occipital somites 1 to 3 migrate to the region of the aorticopulmonary septum. Bilateral removal of this neural crest population prior to migration causes malformation of the aorticopulmonary septum resulting in common arterial outflow channels or transposition of the great vessels.
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