From birth to death: the complex lives of eukaryotic mRNAs
MJ Moore - Science, 2005 - science.org
Science, 2005•science.org
Recent work indicates that the posttranscriptional control of eukaryotic gene expression is
much more elaborate and extensive than previously thought, with essentially every step of
messenger RNA (mRNA) metabolism being subject to regulation in an mRNA-specific
manner. Thus, a comprehensive understanding of eukaryotic gene expression requires an
appreciation for how the lives of mRNAs are influenced by a wide array of diverse regulatory
mechanisms.
much more elaborate and extensive than previously thought, with essentially every step of
messenger RNA (mRNA) metabolism being subject to regulation in an mRNA-specific
manner. Thus, a comprehensive understanding of eukaryotic gene expression requires an
appreciation for how the lives of mRNAs are influenced by a wide array of diverse regulatory
mechanisms.
Recent work indicates that the posttranscriptional control of eukaryotic gene expression is much more elaborate and extensive than previously thought, with essentially every step of messenger RNA (mRNA) metabolism being subject to regulation in an mRNA-specific manner. Thus, a comprehensive understanding of eukaryotic gene expression requires an appreciation for how the lives of mRNAs are influenced by a wide array of diverse regulatory mechanisms.
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