The diseases of the intrahepatic biliary tree are a large group of potentially evolutive
congenital and acquired liver disorders affecting both the adult and pediatric populations.
They represent a relevant cause of liver-related morbidity and mortality and an important
indication for liver transplantation, particularly in children. While the practical approach to
patients affected by biliary tree diseases has not significantly changed yet, the conceptual
approach to the pathophysiology of cholangiopathies has witnessed important advances …